Interaction of polycyclic aromatic hydrocarbons with human cytochrome P450 1B1 in inhibiting catalytic activity.

Shimada T, Murajama N, Tanaka K, Takenaka S, Imai Y, Hopkins NE, Foroozesh MK, Alworth WL, Yamazaki H, Guengerich FP, Komori M
Chem Res Toxicol. 2008 21 (12): 2313-23

PMID: 19548353 · PMCID: PMC2772130 · DOI:10.1021/tx8002998

MeSH Terms (9)

Aryl Hydrocarbon Hydroxylases Computer Simulation Cytochrome P-450 CYP1A1 Cytochrome P-450 CYP1B1 Enzyme Inhibitors Humans Models, Molecular Polycyclic Aromatic Hydrocarbons Protein Conformation

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