The organic cation transporter, OCTN1, expressed in the human heart, potentiates antagonism of the HERG potassium channel.

McBride BF, Yang T, Liu K, Urban TJ, Giacomini KM, Kim RB, Roden DM
J Cardiovasc Pharmacol. 2009 54 (1): 63-71

PMID: 19528813 · PMCID: PMC3745652 · DOI:10.1097/FJC.0b013e3181abc288

MeSH Terms (19)

Anti-Arrhythmia Agents Arrhythmias, Cardiac Cation Transport Proteins Electrophysiology Ether-A-Go-Go Potassium Channels Flecainide Gene Expression Heart Humans Immunohistochemistry Inhibitory Concentration 50 In Situ Hybridization Myocytes, Cardiac Organic Cation Transport Proteins Patch-Clamp Techniques Potassium Channels Quinidine Sulfonamides Symporters

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