RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility.

Larrea MD, Hong F, Wander SA, da Silva TG, Helfman D, Lannigan D, Smith JA, Slingerland JM
Proc Natl Acad Sci U S A. 2009 106 (23): 9268-73

PMID: 19470470 · PMCID: PMC2695095 · DOI:10.1073/pnas.0805057106

MeSH Terms (13)

Actins Cell Line, Tumor Cell Movement Cyclin-Dependent Kinase Inhibitor p27 Cytoplasm G1 Phase Humans Intracellular Signaling Peptides and Proteins MAP Kinase Signaling System Phosphorylation rhoA GTP-Binding Protein Ribosomal Protein S6 Kinases, 90-kDa Signal Transduction

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