Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulators (PAMs).

Engers DW, Niswender CM, Weaver CD, Jadhav S, Menon UN, Zamorano R, Conn PJ, Lindsley CW, Hopkins CR
J Med Chem. 2009 52 (14): 4115-8

PMID: 19469556 · PMCID: PMC2765192 · DOI:10.1021/jm9005065

MeSH Terms (8)

Allosteric Regulation Amides Animals Cell Line Humans Rats Receptors, Metabotropic Glutamate Structure-Activity Relationship

Connections (5)

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