A novel class of H3 antagonists derived from the natural product guided synthesis of unnatural analogs of the marine bromopyrrole alkaloid dispyrin.

Kennedy JP, Conn PJ, Lindsley CW
Bioorg Med Chem Lett. 2009 19 (12): 3204-8

PMID: 19443215 · PMCID: PMC4793969 · DOI:10.1016/j.bmcl.2009.04.106

MeSH Terms (13)

Alkaloids Animals Biological Products Bromine Histamine H3 Antagonists Humans Inhibitory Concentration 50 Porifera Pyrroles Receptors, Histamine H3 Structure-Activity Relationship Sympathomimetics Tyramine

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