Reducing the activity and secretion of microbial antioxidants enhances the immunogenicity of BCG.

Sadagopal S, Braunstein M, Hager CC, Wei J, Daniel AK, Bochan MR, Crozier I, Smith NE, Gates HO, Barnett L, Van Kaer L, Price JO, Blackwell TS, Kalams SA, Kernodle DS
PLoS One. 2009 4 (5): e5531

PMID: 19436730 · PMCID: PMC2677452 · DOI:10.1371/journal.pone.0005531

MeSH Terms (17)

Adjuvants, Immunologic Animals Antioxidants BCG Vaccine CD4-Positive T-Lymphocytes Chemokine CCL5 Immunization, Secondary Interleukin-2 Interleukin-12 Subunit p40 Interleukins Mice Mice, Inbred C57BL Mycobacterium tuberculosis Oxidative Stress RNA, Messenger T-Lymphocytes Tuberculosis, Pulmonary

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