Host deficiency in Vav2/3 guanine nucleotide exchange factors impairs tumor growth, survival, and angiogenesis in vivo.

Brantley-Sieders DM, Zhuang G, Vaught D, Freeman T, Hwang Y, Hicks D, Chen J
Mol Cancer Res. 2009 7 (5): 615-23

PMID: 19435813 · PMCID: PMC2739740 · DOI:10.1158/1541-7786.MCR-08-0401

MeSH Terms (19)

Animals Carcinoma, Lewis Lung Cell Line, Tumor Cell Movement Cell Proliferation Cell Survival Coculture Techniques Endothelial Cells Melanoma, Experimental Mice Mice, Inbred C57BL Mice, Knockout Mice, Nude Neoplasms, Experimental Neovascularization, Pathologic Proto-Oncogene Proteins c-vav Transplantation, Homologous Tumor Burden von Willebrand Factor

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