Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers.

Vilar M, Charalampopoulos I, Kenchappa RS, Simi A, Karaca E, Reversi A, Choi S, Bothwell M, Mingarro I, Friedman WJ, Schiavo G, Bastiaens PI, Verveer PJ, Carter BD, Ibáñez CF
Neuron. 2009 62 (1): 72-83

PMID: 19376068 · PMCID: PMC2810632 · DOI:10.1016/j.neuron.2009.02.020

MeSH Terms (29)

Animals Animals, Newborn Binding Sites Cell Death Cells, Cultured Chlorocebus aethiops Cysteine Green Fluorescent Proteins Humans Membrane Proteins Mice Mutation Nerve Growth Factor Nerve Tissue Proteins Neurons NF-kappa B Oligopeptides Protein Binding Protein Conformation Protein Multimerization Rats Receptor, Nerve Growth Factor Receptors, Growth Factor Receptors, Nerve Growth Factor rhoA GTP-Binding Protein RNA, Small Interfering Signal Transduction Superior Cervical Ganglion Transfection

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