The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1.

Thomas PG, Dash P, Aldridge JR, Ellebedy AH, Reynolds C, Funk AJ, Martin WJ, Lamkanfi M, Webby RJ, Boyd KL, Doherty PC, Kanneganti TD
Immunity. 2009 30 (4): 566-75

PMID: 19362023 · PMCID: PMC2765464 · DOI:10.1016/j.immuni.2009.02.006

MeSH Terms (14)

Animals Antigen-Presenting Cells Carrier Proteins Caspase 1 Cells, Cultured Gene Expression Regulation Genetic Predisposition to Disease Immunity, Innate Influenza A virus Interleukin-1beta Mice Mice, Inbred C57BL Mice, Knockout NLR Family, Pyrin Domain-Containing 3 Protein

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