A potential role for reactive oxygen species and the HIF-1alpha-VEGF pathway in hypoxia-induced pulmonary vascular leak.

Irwin DC, McCord JM, Nozik-Grayck E, Beckly G, Foreman B, Sullivan T, White M, T Crossno J, Bailey D, Flores SC, Majka S, Klemm D, van Patot MC
Free Radic Biol Med. 2009 47 (1): 55-61

PMID: 19358884 · PMCID: PMC2689923 · DOI:10.1016/j.freeradbiomed.2009.03.027

MeSH Terms (18)

Active Transport, Cell Nucleus Animals Antioxidants Capillary Permeability Cell Nucleus Cells, Cultured Endothelium, Vascular Hypoxia Hypoxia-Inducible Factor 1, alpha Subunit Male Mice Mice, Inbred C57BL Pulmonary Artery Reactive Oxygen Species RNA, Small Interfering Signal Transduction Transcriptional Activation Vascular Endothelial Growth Factor A

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