The neuromediator glutamate, through specific substrate interactions, enhances mitochondrial ATP production and reactive oxygen species generation in nonsynaptic brain mitochondria.

Panov A, Schonfeld P, Dikalov S, Hemendinger R, Bonkovsky HL, Brooks BR
J Biol Chem. 2009 284 (21): 14448-56

PMID: 19304986 · PMCID: PMC2682893 · DOI:10.1074/jbc.M900985200

MeSH Terms (20)

Adenosine Triphosphate Animals Brain Cell Respiration Glutamic Acid Hydrogen Peroxide Male Mitochondria Mitochondria, Heart Models, Biological Neurons Oxidation-Reduction Pyruvic Acid Rats Rats, Sprague-Dawley Reactive Oxygen Species Serum Albumin, Bovine Substrate Specificity Succinates Synapses

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