Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization.

Gama V, Gomez JA, Mayo LD, Jackson MW, Danielpour D, Song K, Haas AL, Laughlin MJ, Matsuyama S
Cell Death Differ. 2009 16 (5): 758-69

PMID: 19247369 · PMCID: PMC2669846 · DOI:10.1038/cdd.2009.6

MeSH Terms (16)

Antigens, Nuclear Apoptosis bcl-2-Associated X Protein Cell Line Cell Survival DNA-Binding Proteins HeLa Cells Humans Ku Autoantigen Phosphorylation Proto-Oncogene Proteins c-akt Proto-Oncogene Proteins c-mdm2 RNA, Small Interfering Tumor Suppressor Protein p53 Ubiquitination Vascular Endothelial Growth Factor A

Connections (1)

This publication is referenced by other Labnodes entities:

Links