Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African americans.

Haas DW, Gebretsadik T, Mayo G, Menon UN, Acosta EP, Shintani A, Floyd M, Stein CM, Wilkinson GR
J Infect Dis. 2009 199 (6): 872-80

PMID: 19239339 · PMCID: PMC2784690 · DOI:10.1086/597125

MeSH Terms (17)

Alkynes Anti-HIV Agents Area Under Curve Aryl Hydrocarbon Hydroxylases Benzoxazines Blacks Cyclopropanes Cytochrome P-450 CYP2B6 Genotype HIV Seronegativity Humans Linkage Disequilibrium Metabolic Clearance Rate Nevirapine Oxidoreductases, N-Demethylating Polymorphism, Genetic Safety

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