A chimeric A2 strain of respiratory syncytial virus (RSV) with the fusion protein of RSV strain line 19 exhibits enhanced viral load, mucus, and airway dysfunction.

Moore ML, Chi MH, Luongo C, Lukacs NW, Polosukhin VV, Huckabee MM, Newcomb DC, Buchholz UJ, Crowe JE, Goleniewska K, Williams JV, Collins PL, Peebles RS
J Virol. 2009 83 (9): 4185-94

PMID: 19211758 · PMCID: PMC2668460 · DOI:10.1128/JVI.01853-08

MeSH Terms (15)

Animals Base Sequence Cell Line, Tumor Genome, Viral Humans Interleukin-13 Mice Mice, Inbred BALB C Mucus Mutation Recombinant Fusion Proteins Respiratory Syncytial Viruses Respiratory Syncytial Virus Infections RNA Viral Load

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