Quantitative assessment of DTI-based muscle fiber tracking and optimal tracking parameters.

Heemskerk AM, Sinha TK, Wilson KJ, Ding Z, Damon BM
Magn Reson Med. 2009 61 (2): 467-72

PMID: 19161166 · PMCID: PMC2632726 · DOI:10.1002/mrm.21819

Diffusion tensor imaging-based fiber tracking in skeletal muscle has been used to reconstruct and quantify muscle architecture. In addition, the consistent pattern of muscle fiber geometry enables a quantitative assessment of the fiber tracking. This work describes a method to determine the accuracy of individual muscle fiber tracts based on the location at which the fibers terminate, the fiber path, and similarity to the neighboring fibers. In addition, the effect of different stop criteria settings on this quantitative assessment was investigated. Fiber tracking was performed on the tibialis anterior muscle of nine healthy subjects. Complete fiber tracts covered 89.4 +/- 9.6% and 75.0 +/- 15.2% of the aponeurosis area in the superficial and deep compartments, respectively. Applications of the method include the exclusion of erroneous fiber-tracking results, quantitative assessment of data set quality, and the assessment of fiber-tracking stop criteria.

Copyright 2009 Wiley-Liss, Inc.

MeSH Terms (10)

Algorithms Diffusion Magnetic Resonance Imaging Humans Image Enhancement Image Interpretation, Computer-Assisted Imaging, Three-Dimensional Muscle Fibers, Skeletal Pattern Recognition, Automated Reproducibility of Results Sensitivity and Specificity

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