Long-term exposure to AZT, but not d4T, increases endothelial cell oxidative stress and mitochondrial dysfunction.

Kline ER, Bassit L, Hernandez-Santiago BI, Detorio MA, Liang B, Kleinhenz DJ, Walp ER, Dikalov S, Jones DP, Schinazi RF, Sutliff RL
Cardiovasc Toxicol. 2009 9 (1): 1-12

PMID: 19067249 · PMCID: PMC2714048 · DOI:10.1007/s12012-008-9029-8

MeSH Terms (19)

Biomarkers Cell Death Cell Line, Tumor Cells, Cultured DNA, Mitochondrial Endothelial Cells Glutathione Humans Lactic Acid Membrane Potential, Mitochondrial Mitochondria Mitochondria, Liver Oxidative Stress Phosphorylation Reverse Transcriptase Inhibitors Stavudine Superoxides Time Factors Zidovudine

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