Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity.

Marlo JE, Niswender CM, Days EL, Bridges TM, Xiang Y, Rodriguez AL, Shirey JK, Brady AE, Nalywajko T, Luo Q, Austin CA, Williams MB, Kim K, Williams R, Orton D, Brown HA, Lindsley CW, Weaver CD, Conn PJ
Mol Pharmacol. 2009 75 (3): 577-88

PMID: 19047481 · PMCID: PMC2684909 · DOI:10.1124/mol.108.052886

MeSH Terms (12)

Allosteric Regulation Animals Binding, Competitive Cells, Cultured CHO Cells Cricetinae Cricetulus Dose-Response Relationship, Drug Humans Muscarinic Agonists Rats Receptor, Muscarinic M1

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