The ARF tumor suppressor can promote the progression of some tumors.

Humbey O, Pimkina J, Zilfou JT, Jarnik M, Dominguez-Brauer C, Burgess DJ, Eischen CM, Murphy ME
Cancer Res. 2008 68 (23): 9608-13

PMID: 19047137 · PMCID: PMC2637809 · DOI:10.1158/0008-5472.CAN-08-2263

MeSH Terms (15)

Animals Autophagy Cyclin-Dependent Kinase Inhibitor p16 Disease Progression Fibroblasts Genes, Tumor Suppressor Gene Silencing Humans Lymphoma, B-Cell Mice Mice, Knockout Mice, SCID RNA, Messenger Tumor Suppressor Protein p53 Up-Regulation

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