Induced autoimmunity to heat shock proteins elicits glaucomatous loss of retinal ganglion cell neurons via activated T-cell-derived fas-ligand.

Wax MB, Tezel G, Yang J, Peng G, Patil RV, Agarwal N, Sappington RM, Calkins DJ
J Neurosci. 2008 28 (46): 12085-96

PMID: 19005073 · PMCID: PMC2683273 · DOI:10.1523/JNEUROSCI.3200-08.2008

MeSH Terms (22)

Animals Animals, Newborn Apoptosis Autoantibodies Autoimmune Diseases of the Nervous System Autoimmunity Cell Line Fas Ligand Protein fas Receptor Glaucoma Heat-Shock Proteins Intraocular Pressure Lymphocyte Activation Male Microglia Nerve Degeneration Rats Rats, Inbred Lew Rats, Sprague-Dawley Retinal Degeneration Retinal Ganglion Cells T-Lymphocytes

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