Mice with heterozygous deficiency of lipoic acid synthase have an increased sensitivity to lipopolysaccharide-induced tissue injury.

Yi X, Kim K, Yuan W, Xu L, Kim HS, Homeister JW, Key NS, Maeda N
J Leukoc Biol. 2009 85 (1): 146-53

PMID: 18845616 · PMCID: PMC2626770 · DOI:10.1189/jlb.0308161

MeSH Terms (17)

Animals Cytokines E-Selectin Energy Metabolism Heterozygote Lipopolysaccharides Liver Lung Mice Mice, Transgenic NF-kappa B Oxidative Stress Sepsis Sulfurtransferases Thioctic Acid Tumor Necrosis Factor-alpha Vascular Cell Adhesion Molecule-1

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