Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4.

Niswender CM, Johnson KA, Weaver CD, Jones CK, Xiang Z, Luo Q, Rodriguez AL, Marlo JE, de Paulis T, Thompson AD, Days EL, Nalywajko T, Austin CA, Williams MB, Ayala JE, Williams R, Lindsley CW, Conn PJ
Mol Pharmacol. 2008 74 (5): 1345-58

PMID: 18664603 · PMCID: PMC2574552 · DOI:10.1124/mol.108.049551

MeSH Terms (16)

Allosteric Regulation Animals Antiparkinson Agents CHO Cells Corpus Striatum Cricetinae Cricetulus Humans Injections, Intraventricular In Vitro Techniques Male Parkinson Disease Rats Rats, Sprague-Dawley Receptors, Metabotropic Glutamate Structure-Activity Relationship

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