Rearrangement of the (6S,8R,11S) and (6R,8S,11R) exocyclic 1,N2-deoxyguanosine adducts of trans-4-hydroxynonenal to N2-deoxyguanosine cyclic hemiacetal adducts when placed complementary to cytosine in duplex DNA.

Huang H, Wang H, Qi N, Kozekova A, Rizzo CJ, Stone MP
J Am Chem Soc. 2008 130 (33): 10898-906

PMID: 18661996 · PMCID: PMC2646763 · DOI:10.1021/ja801824b

MeSH Terms (12)

Aldehydes Cytosine Deoxyguanosine DNA DNA Adducts Gene Rearrangement Magnetic Resonance Spectroscopy Nucleic Acid Conformation Nucleotides Reference Standards Sensitivity and Specificity Stereoisomerism

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