Aprotinin exerts differential and dose-dependent effects on myocardial contractility, oxidative stress, and cytokine release after ischemia-reperfusion.

McEvoy MD, Taylor AG, Zavadzkas JA, Mains IM, Ford RL, Stroud RE, Jeffords LB, Beck CU, Reeves ST, Spinale FG
Ann Thorac Surg. 2008 86 (2): 568-75

PMID: 18640335 · PMCID: PMC2675543 · DOI:10.1016/j.athoracsur.2008.04.025

MeSH Terms (18)

Animals Aprotinin Cardiac Surgical Procedures Disease Models, Animal Dose-Response Relationship, Drug Elasticity Image Processing, Computer-Assisted Interleukin-6 Mice Mice, Inbred Strains Myocardial Contraction Myocardial Reperfusion Injury Myocardium Oxidative Stress Peroxidase Serine Proteinase Inhibitors Tumor Necrosis Factor-alpha Ventricular Function, Left

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