Transporter-mediated protection against thiopurine-induced hematopoietic toxicity.

Krishnamurthy P, Schwab M, Takenaka K, Nachagari D, Morgan J, Leslie M, Du W, Boyd K, Cheok M, Nakauchi H, Marzolini C, Kim RB, Poonkuzhali B, Schuetz E, Evans W, Relling M, Schuetz JD
Cancer Res. 2008 68 (13): 4983-9

PMID: 18593894 · PMCID: PMC3323115 · DOI:10.1158/0008-5472.CAN-07-6790

MeSH Terms (21)

Alleles Animals Cell Membrane Cells, Cultured Cytoprotection Drug Resistance, Neoplasm Hematologic Diseases Hematopoiesis Humans Leukemia, Myeloid, Acute Membrane Transport Proteins Mercaptopurine Mice Mice, Knockout Models, Biological Multidrug Resistance-Associated Proteins Polymorphism, Single Nucleotide Purines Sulfhydryl Compounds Survival Analysis Tissue Distribution

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