Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells.

Mudhasani R, Zhu Z, Hutvagner G, Eischen CM, Lyle S, Hall LL, Lawrence JB, Imbalzano AN, Jones SN
J Cell Biol. 2008 181 (7): 1055-63

PMID: 18591425 · PMCID: PMC2442212 · DOI:10.1083/jcb.200802105

MeSH Terms (14)

Animals Cell Proliferation Cells, Cultured Cellular Senescence Cyclin-Dependent Kinase Inhibitor p16 DNA Damage Embryo, Mammalian Fibroblasts Gene Deletion Mice MicroRNAs Ribonuclease III Signal Transduction Tumor Suppressor Protein p53

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