Reduction of Ptf1a gene dosage causes pancreatic hypoplasia and diabetes in mice.

Fukuda A, Kawaguchi Y, Furuyama K, Kodama S, Horiguchi M, Kuhara T, Kawaguchi M, Terao M, Doi R, Wright CV, Hoshino M, Chiba T, Uemoto S
Diabetes. 2008 57 (9): 2421-31

PMID: 18591390 · PMCID: PMC2518493 · DOI:10.2337/db07-1558

MeSH Terms (19)

Animals Body Size Cell Division Diabetes Mellitus, Type 1 Duodenum Gene Dosage Gene Expression Regulation, Developmental Glucose Intolerance Homeodomain Proteins Insulin Insulin Secretion Islets of Langerhans Mice Mice, Inbred C57BL Mice, Mutant Strains Pancreas, Exocrine Stem Cells Trans-Activators Transcription Factors

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