A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function.

Pearson T, Shultz LD, Lief J, Burzenski L, Gott B, Chase T, Foreman O, Rossini AA, Bottino R, Trucco M, Greiner DL
Diabetologia. 2008 51 (8): 1449-56

PMID: 18563383 · PMCID: PMC2719841 · DOI:10.1007/s00125-008-1057-1

MeSH Terms (14)

Animals Cord Blood Stem Cell Transplantation Disease Models, Animal Humans Hyperglycemia Insulin-Secreting Cells Islets of Langerhans Islets of Langerhans Transplantation Mice Mice, Inbred NOD Mutation Receptors, Interleukin-2 Severe Combined Immunodeficiency Transplantation, Heterologous

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