Defective generation of a humoral immune response is associated with a reduced incidence and severity of collagen-induced arthritis in microsomal prostaglandin E synthase-1 null mice.

Kojima F, Kapoor M, Yang L, Fleishaker EL, Ward MR, Monrad SU, Kottangada PC, Pace CQ, Clark JA, Woodward JG, Crofford LJ
J Immunol. 2008 180 (12): 8361-8

PMID: 18523303 · PMCID: PMC2435291 · DOI:10.4049/jimmunol.180.12.8361

MeSH Terms (20)

Animals Arthritis, Experimental Cattle Collagen Type II Cyclooxygenase 1 Cyclooxygenase 2 Female Gene Deletion Genetic Carrier Screening Immunoglobulin G Immunoglobulin M Incidence Male Membrane Proteins Mice Mice, Inbred DBA Mice, Knockout Microsomes RNA, Messenger Severity of Illness Index

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