Cyclin-dependent kinase inhibitor, p21WAF1/CIP1, is involved in adipocyte differentiation and hypertrophy, linking to obesity, and insulin resistance.

Inoue N, Yahagi N, Yamamoto T, Ishikawa M, Watanabe K, Matsuzaka T, Nakagawa Y, Takeuchi Y, Kobayashi K, Takahashi A, Suzuki H, Hasty AH, Toyoshima H, Yamada N, Shimano H
J Biol Chem. 2008 283 (30): 21220-9

PMID: 18445590 · PMCID: PMC3258954 · DOI:10.1074/jbc.M801824200

MeSH Terms (15)

3T3 Cells Adipocytes Animals Apoptosis Cell Differentiation Cell Proliferation Cyclin-Dependent Kinase Inhibitor p21 Hypertrophy Insulin Resistance Mice Mice, Inbred C57BL Mice, Transgenic Models, Biological Obesity Tumor Suppressor Protein p53

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