The apolipoprotein E-mimetic peptide COG112 inhibits the inflammatory response to Citrobacter rodentium in colonic epithelial cells by preventing NF-kappaB activation.

Singh K, Chaturvedi R, Asim M, Barry DP, Lewis ND, Vitek MP, Wilson KT
J Biol Chem. 2008 283 (24): 16752-61

PMID: 18417477 · PMCID: PMC2423260 · DOI:10.1074/jbc.M710530200

MeSH Terms (15)

Animals Apolipoproteins E Citrobacter rodentium Colon Dose-Response Relationship, Drug Epithelial Cells Escherichia coli I-kappa B Kinase Inflammation Mice Models, Biological NF-kappa B NF-kappa B p50 Subunit Nitric Oxide Synthase Type II Peptides

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