c-Myc represses FOXO3a-mediated transcription of the gene encoding the p27(Kip1) cyclin dependent kinase inhibitor.

Chandramohan V, Mineva ND, Burke B, Jeay S, Wu M, Shen J, Yang W, Hann SR, Sonenshein GE
J Cell Biochem. 2008 104 (6): 2091-106

PMID: 18393360 · DOI:10.1002/jcb.21765

MeSH Terms (18)

Animals Apoptosis Binding Sites Cell Line Cyclin-Dependent Kinase Inhibitor p27 Forkhead Box Protein O3 Forkhead Transcription Factors Gene Expression Regulation, Neoplastic Humans Mice Neoplasms Promoter Regions, Genetic Protein Binding Protein Structure, Tertiary Proto-Oncogene Proteins c-myc Repressor Proteins RNA, Messenger Transcription, Genetic

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