The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor.

Schlisio S, Kenchappa RS, Vredeveld LC, George RE, Stewart R, Greulich H, Shahriari K, Nguyen NV, Pigny P, Dahia PL, Pomeroy SL, Maris JM, Look AT, Meyerson M, Peeper DS, Carter BD, Kaelin WG
Genes Dev. 2008 22 (7): 884-93

PMID: 18334619 · PMCID: PMC2279200 · DOI:10.1101/gad.1648608

MeSH Terms (28)

Animals Animals, Newborn Apoptosis Cells, Cultured Child Chromosome Mapping Chromosomes, Mammalian DNA-Binding Proteins HeLa Cells Humans Hypoxia-Inducible Factor-Proline Dioxygenases Immediate-Early Proteins Immunoblotting Kinesins Medulloblastoma Mice Mice, Knockout Models, Biological Mutation, Missense Nerve Tissue Proteins Neuroblastoma Neurons PC12 Cells Pheochromocytoma Procollagen-Proline Dioxygenase Rats RNA Interference Tumor Suppressor Proteins

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