Using 3'-bridging phosphorothiolates to isolate the forward DNA cleavage reaction of human topoisomerase IIalpha.

Deweese JE, Burgin AB, Osheroff N
Biochemistry. 2008 47 (13): 4129-40

PMID: 18318502 · PMCID: PMC2733888 · DOI:10.1021/bi702194x

MeSH Terms (11)

Antigens, Neoplasm Base Sequence DNA DNA-Binding Proteins DNA Primers DNA Topoisomerases, Type II Humans Hydrolysis Kinetics Organophosphorus Compounds Sulfhydryl Compounds

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