, a bio/informatics shared resource is still "open for business" - Visit the CDS website

Contemporary open radical cystectomy: analysis of perioperative outcomes.

Lowrance WT, Rumohr JA, Chang SS, Clark PE, Smith JA, Cookson MS
J Urol. 2008 179 (4): 1313-8; discussion 1318

PMID: 18289578 · DOI:10.1016/j.juro.2007.11.084

PURPOSE - The feasibility of laparoscopic or robotic assisted radical cystectomy has been demonstrated in several small series, but the specific advantages are uncertain and require comparisons to more recent results that incorporate refinements in open technique and perioperative management. We reviewed our contemporary radical cystectomy series to evaluate perioperative outcome measures which could be affected by surgical approach for the purpose of establishing contemporary benchmarks for future comparisons.

MATERIALS AND METHODS - The medical records of 553 consecutive patients undergoing radical cystectomy from January 2000 through June of 2005 were reviewed. Perioperative and demographic data, type of urinary diversion, hospital stay, complications and perioperative mortality were examined.

RESULTS - Median patient age was 69 years (range 22 to 94) and average American Society of Anesthesiologists classification was 2.7. Median operative time was 258 minutes (range 89 to 801). Mean operative time for ileal conduit diversion was 271 vs 312 minutes for neobladder diversion. Median blood loss was 600 ml (range 200 to 4,200). A total of 210 patients (38%) received a blood transfusion either intraoperatively or within the first 30 days of their procedure. Median length of hospital stay was 6 days (range 4 to 79). Minor and major complications occurred in 209 (38%) and 41 (7.4%) patients, respectively. Perioperative mortality was 1.7%.

CONCLUSIONS - These results demonstrate that contemporary radical cystectomy can be accomplished through an open operative approach consistently with acceptable morbidity/mortality and with a median length of stay of less than 1 week. Efforts to further reduce morbidity and improve outcomes should continue.

MeSH Terms (13)

Adult Aged Aged, 80 and over Blood Loss, Surgical Cystectomy Female Humans Length of Stay Male Middle Aged Time Factors Treatment Outcome Urinary Bladder Diseases

Connections (1)

This publication is referenced by other Labnodes entities: