Copper accumulation and lipid oxidation precede inflammation and myelin lesions in N,N-diethyldithiocarbamate peripheral myelinopathy.

Viquez OM, Valentine HL, Amarnath K, Milatovic D, Valentine WM
Toxicol Appl Pharmacol. 2008 229 (1): 77-85

PMID: 18284930 · PMCID: PMC2429851 · DOI:10.1016/j.taap.2008.01.005

MeSH Terms (21)

Animals Brain Chelating Agents Chromatography, High Pressure Liquid Copper Demyelinating Diseases Disease Models, Animal Ditiocarb Immunoglobulin G Lipid Peroxidation Liver Macrophage Activation Macrophages Male Malondialdehyde Mass Spectrometry Oxidative Stress Rats Rats, Sprague-Dawley Sciatic Nerve Tibial Nerve

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