Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles.

Pallan PS, Ittig D, Héroux A, Wawrzak Z, Leumann CJ, Egli M
Chem Commun (Camb). 2008 (7): 883-5

PMID: 18253536 · DOI:10.1039/b716390h

The crystal structure of a DNA duplex with tricyclo-DNA (tc-DNA) residues explains the increased RNA affinity of tc-DNA relative to DNA and tc-DNA's superior resistance to nucleases.

MeSH Terms (6)

Crystallization DNA Hydrogen Bonding Models, Molecular Nucleic Acid Conformation Zinc

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