Covalent modification at Cys151 dissociates the electrophile sensor Keap1 from the ubiquitin ligase CUL3.

Rachakonda G, Xiong Y, Sekhar KR, Stamer SL, Liebler DC, Freeman ML
Chem Res Toxicol. 2008 21 (3): 705-10

PMID: 18251510 · DOI:10.1021/tx700302s

MeSH Terms (17)

Animals Cell Cycle Proteins Cell Line, Tumor Cells, Cultured Chlorocebus aethiops Circular Dichroism COS Cells Cullin Proteins Cysteine DNA, Recombinant Humans Immunoprecipitation Intracellular Signaling Peptides and Proteins Kelch-Like ECH-Associated Protein 1 Kinetics Mass Spectrometry Recombinant Proteins

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