Reversal of blindness in animal models of leber congenital amaurosis using optimized AAV2-mediated gene transfer.

Bennicelli J, Wright JF, Komaromy A, Jacobs JB, Hauck B, Zelenaia O, Mingozzi F, Hui D, Chung D, Rex TS, Wei Z, Qu G, Zhou S, Zeiss C, Arruda VR, Acland GM, Dell'Osso LF, High KA, Maguire AM, Bennett J
Mol Ther. 2008 16 (3): 458-65

PMID: 18209734 · PMCID: PMC2842085 · DOI:10.1038/sj.mt.6300389

MeSH Terms (13)

Animals Blindness Carrier Proteins cis-trans-Isomerases Dependovirus Dogs Electroretinography Eye Proteins Genetic Vectors Immunohistochemistry Mice Mice, Knockout Optic Atrophy, Hereditary, Leber

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