Synthesis and SAR of selective muscarinic acetylcholine receptor subtype 1 (M1 mAChR) antagonists.

Lewis LM, Sheffler D, Williams R, Bridges TM, Kennedy JP, Brogan JT, Mulder MJ, Williams L, Nalywajko NT, Niswender CM, Weaver CD, Conn PJ, Lindsley CW
Bioorg Med Chem Lett. 2008 18 (3): 885-90

PMID: 18178088 · PMCID: PMC2275053 · DOI:10.1016/j.bmcl.2007.12.051

MeSH Terms (12)

Combinatorial Chemistry Techniques Dose-Response Relationship, Drug Dystonia Heterocyclic Compounds Humans Molecular Structure Muscarinic Antagonists Parkinson Disease Receptor, Muscarinic M1 Receptors, G-Protein-Coupled Receptors, Muscarinic Structure-Activity Relationship

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