Legume and soy food intake and the incidence of type 2 diabetes in the Shanghai Women's Health Study.

Villegas R, Gao YT, Yang G, Li HL, Elasy TA, Zheng W, Shu XO
Am J Clin Nutr. 2008 87 (1): 162-7

PMID: 18175751 · PMCID: PMC2361384 · DOI:10.1093/ajcn/87.1.162

BACKGROUND - It has been postulated that a diet high in legumes may be beneficial for the prevention of type 2 diabetes mellitus (type 2 DM). However, data linking type 2 DM risk and legume intake are limited.

OBJECTIVE - The objective of the study was to examine the association between legume and soy food consumption and self-reported type 2 DM.

DESIGN - The study was conducted in a population-based prospective cohort of middle-aged Chinese women. We followed 64,227 women with no history of type 2 DM, cancer, or cardiovascular disease at study recruitment for an average of 4.6 y. Participants completed in-person interviews that collected information on diabetes risk factors, including dietary intake and physical activity in adulthood. Anthropometric measurements were taken. Dietary intake was assessed with a validated food-frequency questionnaire at the baseline survey and at the first follow-up survey administered 2-3 y after study recruitment.

RESULTS - We observed an inverse association between quintiles of total legume intake and 3 mutually exclusive legume groups (peanuts, soybeans, and other legumes) and type 2 DM incidence. The multivariate-adjusted relative risk of type 2 DM for the upper quintile compared with the lower quintile was 0.62 (95% CI: 0.51, 0.74) for total legumes and 0.53 (95% CI: 0.45, 0.62) for soybeans. The association between soy products (other than soy milk) and soy protein consumption (protein derived from soy beans and their products) with type 2 DM was not significant.

CONCLUSIONS - Consumption of legumes, soybeans in particular, was inversely associated with the risk type 2 DM.

MeSH Terms (20)

Adult China Cohort Studies Confidence Intervals Diabetes Mellitus, Type 2 Fabaceae Female Follow-Up Studies Health Surveys Humans Incidence Middle Aged Multivariate Analysis Nutrition Assessment Odds Ratio Prospective Studies Risk Factors Soy Foods Surveys and Questionnaires Women's Health

Connections (2)

This publication is referenced by other Labnodes entities: