A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulation.

Lin X, David CA, Donnelly JB, Michaelides M, Chandel NS, Huang X, Warrior U, Weinberg F, Tormos KV, Fesik SW, Shen Y
Proc Natl Acad Sci U S A. 2008 105 (1): 174-9

PMID: 18172210 · PMCID: PMC2224181 · DOI:10.1073/pnas.0706585104

MeSH Terms (16)

Acetates Chemistry, Pharmaceutical Gene Library Genomics Genomics Humans Hypoxia Hypoxia-Inducible Factor 1, alpha Subunit Mitochondria Models, Biological Nuclear Proteins Pharmacogenetics Reactive Oxygen Species RNA, Small Interfering Small Molecule Libraries Technology, Pharmaceutical

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