A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene.

King M, Pearson T, Shultz LD, Leif J, Bottino R, Trucco M, Atkinson MA, Wasserfall C, Herold KC, Woodland RT, Schmidt MR, Woda BA, Thompson MJ, Rossini AA, Greiner DL
Clin Immunol. 2008 126 (3): 303-14

PMID: 18096436 · DOI:10.1016/j.clim.2007.11.001

MeSH Terms (15)

Animals Diabetes Mellitus Disease Models, Animal Graft Rejection Humans Interleukin Receptor Common gamma Subunit Islets of Langerhans Islets of Langerhans Transplantation Leukocytes, Mononuclear Mice Mice, Inbred NOD Mice, SCID Mice, Transgenic Mutation Phenotype

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