The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling.

Brantley-Sieders DM, Zhuang G, Hicks D, Fang WB, Hwang Y, Cates JM, Coffman K, Jackson D, Bruckheimer E, Muraoka-Cook RS, Chen J
J Clin Invest. 2008 118 (1): 64-78

PMID: 18079969 · PMCID: PMC2129239 · DOI:10.1172/JCI33154

MeSH Terms (21)

Adenocarcinoma Animals Antigens, Polyomavirus Transforming Breast Neoplasms Cell Movement Cell Proliferation Cell Transformation, Neoplastic Female Humans Male Mammary Glands, Animal Mammary Glands, Human Mammary Neoplasms, Experimental MAP Kinase Signaling System Mice Mice, Transgenic Neoplasm Metastasis Receptor, EphA2 Receptor, ErbB-2 rhoA GTP-Binding Protein rho GTP-Binding Proteins

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