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Histamine directly and synergistically with lipopolysaccharide stimulates cyclooxygenase-2 expression and prostaglandin I(2) and E(2) production in human coronary artery endothelial cells.

Tan X, Essengue S, Talreja J, Reese J, Stechschulte DJ, Dileepan KN
J Immunol. 2007 179 (11): 7899-906

PMID: 18025237 · PMCID: PMC2597490 · DOI:10.4049/jimmunol.179.11.7899

MeSH Terms (23)

Animals Cells, Cultured Coronary Vessels Cyclooxygenase 2 Dinoprostone Dose-Response Relationship, Drug Drug Synergism Endothelial Cells Epoprostenol Gene Expression Regulation Gene Silencing Histamine Humans Lipopolysaccharides Mice Mice, Knockout Oxidoreductases Acting on CH-NH Group Donors Receptors, Histamine H1 Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger RNA, Small Interfering Structure-Activity Relationship Thromboxane A2

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