Novel substituted (Z)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-one and (Z)-(+/-)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-ol derivatives as potent thermal sensitizing agents.

Sonar VN, Thirupathi Reddy Y, Sekhar KR, Sasi S, Freeman ML, Crooks PA
Bioorg Med Chem Lett. 2007 17 (24): 6821-4

PMID: 17980582 · PMCID: PMC3726020 · DOI:10.1016/j.bmcl.2007.10.035

MeSH Terms (8)

Cell Line, Tumor Cell Survival Humans Molecular Structure Quinuclidines Radiation-Sensitizing Agents Structure-Activity Relationship Temperature

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