Structure and activity of Y-class DNA polymerase DPO4 from Sulfolobus solfataricus with templates containing the hydrophobic thymine analog 2,4-difluorotoluene.

Irimia A, Eoff RL, Pallan PS, Guengerich FP, Egli M
J Biol Chem. 2007 282 (50): 36421-33

PMID: 17951245 · DOI:10.1074/jbc.M707267200

MeSH Terms (12)

Bacterial Proteins Crystallography, X-Ray DNA, Bacterial DNA Polymerase beta Hydrophobic and Hydrophilic Interactions Kinetics Nucleotides Protein Structure, Tertiary Structure-Activity Relationship Sulfolobus solfataricus Thymine Toluene

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