Kidney-specific inactivation of the Pkd1 gene induces rapid cyst formation in developing kidneys and a slow onset of disease in adult mice.

Lantinga-van Leeuwen IS, Leonhard WN, van der Wal A, Breuning MH, de Heer E, Peters DJ
Hum Mol Genet. 2007 16 (24): 3188-96

PMID: 17932118 · DOI:10.1093/hmg/ddm299

MeSH Terms (19)

Age of Onset Animals Animals, Newborn Animals, Suckling Cell Proliferation Cysts Gene Deletion Gene Expression Regulation Germ-Line Mutation Kidney Lactation Mice Mice, Transgenic Models, Biological Organ Specificity Polycystic Kidney Diseases Tamoxifen Time Factors TRPP Cation Channels

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