Ligand-independent phosphorylation of Y869 (Y845) links mutant EGFR signaling to stat-mediated gene expression.

Yang S, Park K, Turkson J, Arteaga CL
Exp Cell Res. 2008 314 (2): 413-9

PMID: 17927978 · PMCID: PMC3221731 · DOI:10.1016/j.yexcr.2007.09.002

MeSH Terms (12)

ErbB Receptors Erlotinib Hydrochloride Genes, myc Humans Ligands Mutation Phosphorylation Proto-Oncogene Proteins pp60(c-src) Quinazolines Signal Transduction STAT5 Transcription Factor Tumor Cells, Cultured

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