The Drosophila homolog of MCPH1, a human microcephaly gene, is required for genomic stability in the early embryo.

Rickmyre JL, Dasgupta S, Ooi DL, Keel J, Lee E, Kirschner MW, Waddell S, Lee LA
J Cell Sci. 2007 120 (Pt 20): 3565-77

PMID: 17895362 · DOI:10.1242/jcs.016626

MeSH Terms (16)

Animals Cell Cycle Cell Cycle Proteins Checkpoint Kinase 1 Checkpoint Kinase 2 Chromatin Drosophila melanogaster Drosophila Proteins Embryo, Nonmammalian Genes, Insect Genomic Instability Mitosis Mushroom Bodies Mutation Protein-Serine-Threonine Kinases Protein Kinases

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