AFAP-110 is overexpressed in prostate cancer and contributes to tumorigenic growth by regulating focal contacts.

Zhang J, Park SI, Artime MC, Summy JM, Shah AN, Bomser JA, Dorfleutner A, Flynn DC, Gallick GE
J Clin Invest. 2007 117 (10): 2962-73

PMID: 17885682 · PMCID: PMC1978423 · DOI:10.1172/JCI30710

MeSH Terms (21)

Animals Carcinoma Cell Adhesion Cell Line, Tumor Cell Movement Cell Proliferation Cell Transformation, Neoplastic Down-Regulation Extracellular Matrix Focal Adhesions Humans Integrins Male Mice Mice, Nude Microfilament Proteins Mutation Phosphoproteins Prostatic Neoplasms Protein-Tyrosine Kinases Up-Regulation

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